Scientists step closer to Alzheimer's blood test (University of Newcastle Research)

An interdisciplinary team of scientists at the University of Newcastle has shown the potential of a simple blood-based test to identify people in the early stages of Alzheimer’s disease, before any symptoms appear. The team of four spent a year studying data from the international Alzheimer’s Disease Neuroimaging Initiative (ADNI) database, the most comprehensive collection of Alzheimer’s data in the world.

The Newcastle team assessed the levels of 190 proteins in blood from 566 people with either Alzheimer’s Disease, mild cognitive impairment or normal cognition and showed that measuring a panel of 11 proteins in blood can provide a predictive test with more than 85 per cent accuracy. Monitoring the change in blood protein levels over time could increase accuracy above 90 per cent.

The study's findings are published in the prestigious PLoS ONE journal.

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